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When a soft mattress levitates the sleeper…

Publication Research On May 21, 2025

In a recent work, researchers show that particles entrained in a flow close to a deformable wall undergo a force that moves them slightly away from it, an important result for the general understanding of transport phenomena in biology.

To find out more, take a look at :

AFM

Contact

Abdelhamid MAALI (LOMA, Bordeaux)
abdelhamid.maaliatu-bordeaux.fr (abdelhamid[dot]maali[at]u-bordeaux[dot]fr)

Chaouqi MISBAH (LIPhy, Grenoble)
chaouqi.misbahatuniv-grenoble-alpes.fr (chaouqi[dot]misbah[at]univ-grenoble-alpes[dot]fr) 

Reference

H. Zhang, Z. Zhang, A. Jha, Y. Amarouchene, T. Salez, T. Guérin, C. Misbah and A. Maali. Direct Measurement of the Viscocapillary Lift Force near a Liquid Interface. Physical Review Letters 134(9), 094001 (2025)

The guided journey of male gametes in flowering plants

Publication Research On September 22, 2025

At the heart of the Arabidopsis thaliana flower, the pistil, formed of hundreds of papillae and an ovary housing the ovules, is surrounded by stamens that release pollen grains carrying male gametes. In an article published in PLOS Computational Biology, scientists combine theory and experiments to reveal how male gametes are guided toward the ovules from the very beginning of their journey on the surface of the female reproductive organ.

To find out more, take a look at :

  • the news published on the CNRS Biologie website,
  • the scientific article published in PLOS Computational Biology.
Plante

Contact

Isabelle Fobis-Loisy (ENS Lyon)
isabelle.fobis-loisyatens-lyon.fr (isabelle[dot]fobis-loisy[at]ens-lyon[dot]fr)

Karin John (LIPhy, Grenoble)
karin.johnatuniv-grenoble-alpes.fr (karin[dot]john[at]univ-grenoble-alpes[dot]fr)

Reference

L. Riglet C. Quilliet, C. Godin, K. John, I. Fobis-Loisy. Geometric and mechanical guidance: Role of stigmatic epidermis in early pollen tube pathfinding in arabidopsis. PLoS Computional Biology 21(5) e1013077 (2025)

How cyanobacteria's circadian clock reacts to cold

Publication Research On May 6, 2025

Cyanobacteria have an internal biological clock that rhythms their activities on a 24-hour cycle. Thanks to this finely regulated mechanism, these micro-organisms are able to anticipate day/night cycles. A study recently published in Scientific Reports looked at how this clock reacts when the temperature drops below 25°C, an important threshold for their physiology.

To find out more, take a look at :

Cyanobacteria

Contact

Irina MIHALCESCU
irina.mihalcescuatuniv-grenoble-alpes.fr (irina[dot]mihalcescu[at]univ-grenoble-alpes[dot]fr)

Reference

I. Mihalcescu, H. Kaji, H. Maruyama, J. Giraud, M. Van Melle-Gateau, B. Houchmandzadeh & H. Ito. When lowering temperature, the in vivo circadian clock in cyanobacteria follows and surpasses the in vitro protein clock trough the Hopf bifurcation. Scientific Reports 15(1), 14884 (2025)

Laser microbubbles to test plant cell pressure

Publication Research On May 7, 2025

Using laser nucleation of microbubbles, physicists have shown that stomata, the miniature 'gates' that regulate light-dependent evaporation in vascular plants, remain inactive in non-vascular plants such as mosses.

To find out more, take a look at :

  • the news published on the CNRS Physique website,
  • the scientific article published in Proceedings of the National Academy of Science.
LaserHighSelaginella

Contact

Philippe MARMOTTANT
philippe.marmottantatuniv-grenoble-alpes.fr (philippe[dot]marmottant[at]univ-grenoble-alpes[dot]fr)

Reference

C. R. Brodersen, T. Brodribb, U. Hochberg, N. M. Holbrook, S. A. M. McAdam, J. Zailaa, B. Huggett, P. Marmottant. In-situ cavitation bubble manometry reveals lack of light-activated guard cell turgor modulation in bryophytes. Proceedings of the National Academy of Science 122 (13) e2419887122 (2025)

The interaction between macrophages and their environment affects their functioning

Publication Research On March 27, 2025

Macrophages are immune system cells that ingest and degrade microorganisms and cellular debris in a process called phagocytosis. In a study published in iScience, scientists show that the mechanical properties of the tissues surrounding macrophages influence phagocytosis, which in turn affects the way macrophages interact with their environment.

To find out more, take a look at :

  • the news published on the CNRS Biologie website,
  • the scientific article published in Nature Microbiology.
macrophages

Contact

Isabelle Tardieux (IAB, Grenoble)
isabelle.tardieuxatinserm.fr (isabelle[dot]tardieux[at]inserm[dot]fr)

Galina Dubacheva (DCM, Grenoble)
galina.dubachevaatuniv-grenoble-alpes.fr (galina[dot]dubacheva[at]univ-grenoble-alpes[dot]fr)

Delphine Débarre (LIPhy, Grenoble)
delphine.debarreatuniv-grenoble-alpes.fr (delphine[dot]debarre[at]univ-grenoble-alpes[dot]fr)

 

Reference

L. Vigetti, B. Touquet, L. Bureau, D. Abdallah, I. Tardieux , D. Debarre, T. Rose, G. V. Dubacheva. Submicrometre spatiotemporal characterization of the Toxoplasma adhesion strategy for gliding motility. Nature Microbiology 9, 3148 (2024)

Recording the absorption spectra of gaseous molecules with an optical cavity of high finesse

Publication Research On February 20, 2025

To better understand the formation, composition and evolution of the atmospheres of terrestrial planets, scientists at LIPhy have developed spectrometers using optical cavity spectroscopy (CRDS). Their high sensitivity enables them to accurately record the absorption spectra of various molecules of atmospheric and planetary interest, such as dihydrogen, water or methane, mixed with carbon dioxide.

This research was funded in whole or in part by the French National Research Agency (ANR) under the COMPLEAT project, coordinated by Didier Mondelain, a CNRS researcher at LIPhy.

To find out more, take a look at the article published in "Focus Sciences" of CNRS Le Journal.

Photo_COMPLEAT
© Christian Morel / LIPhy / CNRS Images

Contact

Didier Mondelain
didier.mondelainatuniv-grenoble-alpes.fr (didier[dot]mondelain[at]univ-grenoble-alpes[dot]fr)

Caging bubbles to develop high-resolution microscopes

Publication Research On December 12, 2024

Bubbles are ubiquitous in many research applications, from ultrasound imaging to understanding volcanic eruptions. They are also excellent acoustic resonators, being very small in size compared to the wavelength of the sound they emit. These resonant sound waves contain information about the mechanical properties of materials in the immediate vicinity of the bubble. In a recent publication in Nature Communications, a collaboration between LIPhy's Optima and Move teams proposes to exploit this phenomenon to image a sample by moving a bubble in its vicinity.

To find out more, take a look at :

cage cubique

Contact

Emmanuel Bossy
emmanuel.bossyatuniv-grenoble-alpes.fr (emmanuel[dot]bossy[at]univ-grenoble-alpes[dot]fr)

Scrutinizing the skeleton of our cells, an essential issue for health

Publication Research On November 28, 2024

By combining a numerical modeling approach with experiments in both structural and cellular biology, the APERTuRe project has led to a better understanding of the dynamics of a protein network in the cytoplasm of our cells. These results could prove useful in the development of new drugs.

The project was coordinated by Karin John, a CNRS researcher at LIPhy. To find out more, take a look at the article published in "Focus Sciences" of CNRS Le Journal.

immunofluorescence

Contact

Karin John
karin.johnatuniv-grenoble-alpes.fr (karin[dot]john[at]univ-grenoble-alpes[dot]fr)

The secrets of Toxoplasma gondii parasite movement revealed

Publication Research On November 21, 2024

In an article published in Nature Microbiology, scientists have deciphered the rapid gliding strategy of the parasitic microbe Toxoplasma gondii within the host organism's tissues. They show how the parasite is able to hold on tightly enough without sticking to its substrate to glide efficiently. By explaining how a minimal adhesion system is able to generate rapid movement within complex microenvironments, they open up perspectives for other models of cellular interactions.

To find out more, take a look at :

  • the news published on the CNRS Biologie website,
  • the scientific article published in Nature Microbiology.
toxoplasma

Contact

Isabelle Tardieux (IAB, Grenoble)
isabelle.tardieuxatinserm.fr (isabelle[dot]tardieux[at]inserm[dot]fr)

Galina Dubacheva (DCM, Grenoble)
galina.dubachevaatuniv-grenoble-alpes.fr (galina[dot]dubacheva[at]univ-grenoble-alpes[dot]fr)

Delphine Débarre (LIPhy, Grenoble)
delphine.debarreatuniv-grenoble-alpes.fr (delphine[dot]debarre[at]univ-grenoble-alpes[dot]fr)

 

Reference

L. Vigetti, B. Touquet, L. Bureau, D. Abdallah, I. Tardieux , D. Debarre, T. Rose, G. V. Dubacheva. Submicrometre spatiotemporal characterization of the Toxoplasma adhesion strategy for gliding motility. Nature Microbiology 9, 3148 (2024)

When red blood cells go off the beaten track

Publication Research On November 25, 2024

A Franco-American collaboration has demonstrated that in the microcirculatory network, some red blood cells can take unexpected routes to get from one point to another. This experimental observation should lead to more precise modeling of the mechanisms of oxygenation and elimination of the residues of cellular activity within the blood network.

To find out more, take a look at :

Globules rouges

Contact

Gwennou Coupier (LIPhy)
gwennou.coupieratuniv-grenoble-alpes.fr (gwennou[dot]coupier[at]univ-grenoble-alpes[dot]fr)

Thomas Podgorski (LRP)
thomas.podgorskiatuniv-grenoble-alpes.fr (thomas[dot]podgorski[at]univ-grenoble-alpes[dot]fr)

Reference

M. Alonzo, N. J. Karst, T. Podgorski, J. B. Geddes, and G. Coupier. Spatio-temporal instabilities of blood flow in a model capillary network. Physical Review Fluids 9, 104401 (2024)

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