images of a L5 pyramidal neuron relative to UV (405 nm) illumination spot position
images of a L5 pyramidal neuron relative to UV (405 nm) illumination spot position
PublicationResearch

Controlling ion channel activity with photoactivatable toxins

on the 9 February 2022
Photoactivatable ion channel toxins derived from animal venoms provide the opportunity to control the activity of excitable cells with high spatiotemporal precision. An international consortium including LIPhy researchers has developed a new technology to make these peptides photoactivatable, thus allowing precise spatiotemporal control of neuronal ion channels associated with excitability. This technology opens the door to new opportunities for translational research and therapeutic applications using light.
Mis à jour le 2 June 2022