Microtiss

The MicroTiss team is studying how cells probe and respond to mechanical stimuli.

Cells are individual entities, equipped with dedicated sensors to probe the local chemical and mechanical environment. However, to ensure the functional formation and organization of a tissue, as well as its homeostasis, cells must coordinate at the supracellular level.

To this end, cells must integrate and interpret environmental information over a region much larger than their own size.

Objectives:

• Determine the basic building blocks of cell-cell interactions.
• Understand the collective mechanisms in model tissues
• Establish a multiphase description of 3D tissues

• Regulation of biomechanical in biological tissues

• Techniques for quantitative mechanobiology