Innovation

An artificial pancreas

Innovation On July 2, 2024

A new implantable pancreatic bioreactor device has been developed by the SyNaBi team in the TIMC laboratory (Translational Innovation in Medicine and Complexity), in collaboration with Grenoble Alpes University Hospital and the LIPhy (3D printing) and LBFA (Laboratory of Fundamental and Applied Bioenergetics) laboratories.

This innovative approach is currently in the CNRS maturation phase (since May 2023), through the "BioPI" project: "implantable pancreatic bioreactor". Presented in an issue of CNRS Innovation in 2023, the project was the subject of a new feature in the economics section of the Dauphiné libéré of July 02, 2024.

Like an artificial pancreas, this innovative device will enable healthy insulin-secreting pancreas cells to be implanted, thus modulating blood glucose levels and regulating glycemia in patients suffering from type 1 diabetes. Distributed in a matrix printed by a 3D device produced at LIPhy and isolated by a porous membrane, the pancreatic cells can then be implanted under particularly interesting conditions: by isolating the pancreatic islets thanks to a porous membrane, the bioreactor eliminates the risk of rejection while promoting their oxygenation. The device is being developed in collaboration with Professors Sandrine Lablanche and Pierre Yves Benhamou, two diabetologists at Grenoble Alpes University Hospital.

Project partners:

  • TIMC, SyNaBi team: Abdelkader Zebda, Boudewijn van der Sanden, Ibrahim Shalayel, Nikita Rajkumari, Capucine Arnol and Donald Martin
  • TIMC, BCM team: Angélique Stéphanou
  • LIPhy, MoVe team: Olivier Stephan, Laetitia Gredy
  • LBFA, Diabete cell therapy axis: Emily Tubss, Sandrine Lablanche, Pierre-Yves Benhamou
  • Grenoble Alpes University Hospital:  Sandrine Lablanche and Pierre Yves Benhamou
Equipe_BioPi
The BioPi team includes Ibrahim Shalayel, Clovis Chabert, Olivier Stéphan, Boudewijn Van der Sanden, Sandrine Lablanche, Abdelkader Zebda, and Quentin Perrier. Pierre-Yves Benhamou, who is also taking part in this project, is not in the photo.

Matostheque

Innovation On July 2, 2024

The "matostheque" is an online tool for reserving small items of materials. Materials owners add the characteristics and availability of their material to the database. Users can then make a loan request, specifying the dates.

Software features :

  • detailed description of materials with manuals and specifications
  • QR Code generation for display on material for identification by smartphone
  • optional validation request before each loan
  • notifications of borrowed materials and reminders of return dates
  • calculation of GHG emissions linked to the purchase of material and therefore avoided per loan
Illustrations :

"materiels"
Materials database 

 

menu_matostheque
Interface intuitive

(Inventory: database, My loans: loans in progress, My materials: materials I have added)

 

QR Code displayed on a piece of equipment
matostheque

Plus d'info

Development technology :

Database : Postgresql

Server side : Django

Client side : Nextjs

IT team and nomena.randrianiainaatetu.univ-grenoble-alpes.fr (Nomena Randrianiaina) (contact private mail via ikoriantsouh11atgmail.com (ikoriantsouh11[at]gmail[dot]com), Student : L3 UGA)

Nanofluidics, a path to blue energy

Communiqué Innovation On September 6, 2022

Blue energy from the difference in salinity between fresh river water and salt ocean water is an avenue to explore for the energy transition thanks to the contributions of fundamental research on nanomaterials.

Discover on the CNRS blog "An ocean of discoveries" how research in nanofluidics is making these future technologies possible. At the heart of this research, and of this article, are the teams of Lydéric Bocquet from LPENS and Cyril Picard from the MODI team of LIPhy and the startup Sweetch Energy.

Contact at LIPhy : Cyril.PICARDatuniv-grenoble-alpes.fr (subject: Depuis%20le%20site%20du%20LIPhy) (Cyril Picard)

énergie bleue
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