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Tooth sensitivity, a network issue?

Publication / Research

On July 18, 2025

Tooth

Dental sensitivity is unique in that it is mediated by cells called odontoblasts, located in the dental pulp at the center of the tooth. According to hydrodynamic theory, the activation of odontoblastic processes is linked to the movement of fluids in the dentinal porosity induced by external stimuli. A new study conducted at the Interdisciplinary Laboratory of Physics (LIPhy - CNRS/UGA) shows that this porosity has all the characteristics of a complex network. Far from functioning as independent sensors, odontoblasts could therefore, in theory, adopt collective behaviors that are very different from the simple sum of individual responses.

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Date

On July 18, 2025

Contact

Aurélien GOURRIER
aurelien.gourrieratuniv-grenoble-alpes.fr (aurelien[dot]gourrier[at]univ-grenoble-alpes[dot]fr)

Reference

L. Chatelain, N. Tremblay, E. Vennat, E. Dursun, D. Rousseau & A. Gourrier. Cellular porosity in dentin exhibits complex network characteristics with spatio-temporal fluctuations. PLOS One 20(7), e0327030 (2025)

Submitted on July 18, 2025

Updated on July 28, 2025