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Welcome to LIPhy

The laboratory is a joint CNRS/University of Grenoble Alpes unit and is attached to the Physics, Engineering, Materials pole of the university.  The laboratory is largely oriented towards the interfaces of physics with other disciplines, in particular life sciences and environmental sciences, mechanics or applied mathematics.

 

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Bee intelligence: a scientific revolution

Conference

Bee intelligence: a scientific revolution

On November 27, 2025

As part of the BEECOG project, a scientific collaboration involving LIPhy whose aim is to study the role of cognition -and in particular learning- in the collective behavior of bees, Aurore Avarguès-Weber, CNRS research director at the Centre de Recherches sur la Cognition Animale in Toulouse, will give a public lecture at MaCI on Thursday, November 27, 2025, at 7 p.m.

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An international team of researchers from LIPhy (Université Grenoble Alpes / CNRS), the Institut des Molécules et Matériaux du Mans (Le Mans Université / CNRS) and the Technische Universität Darmstadt (Germany) has shown that copper-based nanoparticles (Cu(OH)₂) can degrade bacterial membranes in presence of small amounts of hydrogen peroxide – amounts comparable to those naturally produced by the metabolism of bacterial cells.

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A team of researchers from ESPCI Paris (CNRS/PSL/Sorbonne Université) and the Laboratoire Interdisciplinaire de Physique (CNRS/Université Grenoble Alpes) combined high-resolution electrostatic mapping with molecular dynamics simulations to investigate the behavior of these surface-trapped ionic charges. They found that the ionic charges spread across the surface with astonishing mobility. Their two-dimensional diffusion far exceeds that of ions in bulk water, with the limiting factor being the friction between the ionic solvation shell and the solid.

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An interdisciplinary team of researchers from Germany and the LIPhy has demonstrated that Tau, a neuronal protein known for stabilizing microtubule tips, plays an active role in modulating microtubule lattice dynamics. The study reveals that Tau significantly accelerates the exchange of tubulin within the microtubule lattice, especially at topological defect sites, despite lacking enzymatic activity. These findings challenge the traditional view of Tau as merely a passive stabilizer, showing instead that it increases lattice anisotropy and, in doing so, actively enhances microtubule lattice dynamics.

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