The secrets of Toxoplasma gondii parasite movement revealed

Publication / Research

On November 21, 2024

In an article published in Nature Microbiology, scientists have deciphered the rapid gliding strategy of the parasitic microbe Toxoplasma gondii within the host organism's tissues. They show how the parasite is able to hold on tightly enough without sticking to its substrate to glide efficiently. By explaining how a minimal adhesion system is able to generate rapid movement within complex microenvironments, they open up perspectives for other models of cellular interactions.

To find out more, take a look at :

the news published on the CNRS Biologie website,
the scientific article published in Nature Microbiology.

Date

On November 21, 2024

Contact

Isabelle Tardieux (IAB, Grenoble)
isabelle.tardieuxinserm.fr (isabelle[dot]tardieux[at]inserm[dot]fr)

Galina Dubacheva (DCM, Grenoble)
galina.dubachevauniv-grenoble-alpes.fr (galina[dot]dubacheva[at]univ-grenoble-alpes[dot]fr)

Delphine Débarre (LIPhy, Grenoble)
delphine.debarreuniv-grenoble-alpes.fr (delphine[dot]debarre[at]univ-grenoble-alpes[dot]fr)

Reference

L. Vigetti, B. Touquet, L. Bureau, D. Abdallah, I. Tardieux , D. Debarre, T. Rose, G. V. Dubacheva. Submicrometre spatiotemporal characterization of the Toxoplasma adhesion strategy for gliding motility. Nature Microbiology 9, 3148 (2024)